Novavax
  • 21-Aug-2017 to 20-Oct-2017 (EST)
  • Vaccine Development
  • Gaithersburg, MD, USA
  • Full Time - Exempt

Novavax, Inc. is a clinical-stage biotechnology company committed to delivering novel products to prevent a broad range of infectious diseases. Using innovative proprietary recombinant nanoparticle vaccine technology, we produce vaccine candidates to efficiently and effectively respond to both known and emerging disease threats. Our vaccine candidates are genetically engineered three-dimensional nanostructures that incorporate recombinant proteins critical to disease pathogenesis.

Our product pipeline targets a variety of infectious diseases, with clinical vaccine candidates for respiratory syncytial virus (RSV) and Ebola virus (EBOV), and preclinical programs for Zika virus (ZIKV), seasonal influenza and a combination respiratory vaccine candidate, as well as other infectious disease vaccine candidates.

Overview:

We are currently seeking a highly motivated scientist to join the Novavax vaccine discovery group. This is a hands-on position with responsibility for protein purification and characterization, protein structure analysis and structure based vaccine antigen design. The right candidate should have an in-depth understanding of genetic engineering, protein chemistry, and structural biology. The ability to understand and interpret complex data is essential and the position requires strong organizational and documentation skills. This position will report to the director of Genetic Engineering.

Responsibilities include but are not limited to:

  • Protein purification to support current and new recombinant vaccine discovery program and reagent generation.
  • Analyze X-ray crystallography and electron microscopy protein structure data to aid rational design of novel vaccine antigen.
  • Characterize vaccine antigen with biochemical, biophysical and immunological methods.
  • Review current scientific literatures for new technologies in vaccine research.
  • Work closely and advise preclinical, product development, analytical development and formulation group.
  • Present scientific findings at internal and external meetings and write research papers.

Minimum Requirements:

  • A Ph.D. in biochemistry or related discipline with at least 2 years of relevant experience.
  • Extensive hands on experience with protein purification techniques including chromatography and filtration. Must be able to operate AKTA Avant instrument.
  • Experience with structure biology techniques including X-ray crystallography and electron microscopy. Must be able to use software to analyze protein structure in depth.
  • Experience with rational vaccine antigen design is preferred.
  • Experience with HPLC is preferred.
  • Knowledge of molecular biology and next generation sequencing is preferred.
  • Experience working with membrane proteins from viruses including influenza, RSV, MERS, Ebola and Zika is preferred.
  • Experience with insect cell and baculovirus expression system is preferred.
  • Knowledge of FDA and ICH regulatory guidelines and cGMP requirements.
  • Demonstration of a strong publication record.
  • Excellent verbal and written communication skills.
  • Must be able to work in a team environment and adapt to changing priorities.

Novavax is headquartered in Gaithersburg, Maryland with additional facilities in Rockville, Maryland and Uppsala, Sweden. Novavax is traded on the Nasdaq Stock Market under the symbol NVAX and is dedicated to developing novel vaccines to address infectious disease.

Novavax, Inc. offers a base salary, annual bonus, stock options, professional career development/growth opportunities, and a comprehensive benefits package including medical, dental, vision, Rx, STD, LTD, Life, Optional Life, 401(k) plan.

We are an equal opportunity employer that values diversity at all levels. All individuals, regardless of personal characteristics, are encouraged to apply.

Novavax
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