• 11-Aug-2017 to 10-Oct-2017 (EST)
  • Analytical Development
  • 20878, MD, USA
  • Full Time - Exempt

Are you ready to work for one of Washington's Top Workplaces?  At Novavax, a clinical-stage vaccine company, we are creating tomorrow's vaccines today! We seek to attract, develop, and retain talented people who share our passion for science, medicine, and human health. We foster an environment of teamwork and collaboration, built on a culture that values and appreciates its employees. We are a fast-paced company that provides employees with opportunities to achieve personal and professional goals while also maintaining a balance between work and personal life.

We are seeking a Scientist I to join the Analytical Development Department in Rockville, MD.  We are looking for a motivated, energetic, and detail oriented individual to work within the Characterization group to provide analytical characterization and comparability assessment of complex adjuvants and protein antigens used in vaccine drug products.  Understanding principals and practical applications of mass spectrometry and biophysical methods for protein characterization is required. The ideal candidate should have a strong background in HPLC, mass spectrometry, AUC, DLS, SPR, UV/Vis, and fluorescence spectroscopy.  Knowledge of glycobiology and experience with carbohydrate analysis is a plus.

Strong assay development, experimental design, and troubleshooting skills are a must.  The ability to work on multiple projects and to clearly communicate results is critical.  The ideal candidate will make detailed observations, analyze data, interpret results, and exercise appropriate technical judgment in the design, execution, and interpretation of experimental data.  The candidate will receive guidance from a supervisor for routine work and new assignments.

Responsibilities include but not limited to:  

  • Perform analytical testing of protein antigens using LC-MS and spectroscopic methods to establish purity/impurity profile.
  • Characterize complex adjuvants and protein antigens using new cutting-edge LC-MS and biophysical technologies.
  • Perform analytical testing as part of characterization and comparability studies to support regulatory requirements.
  • Author/ co-author and review reports and SOPs
  • Support Discovery testing needs for the projects in the pipeline
  • Perform method qualification, and method transfer to other departments (e.g. QC)
  • Thoroughly analyze results and methods, solve analytical problems, and troubleshoot assays
  • Prepare scientific journal publications and presentations
  • Present scientific findings at internal meetings and external conferences

Minimum Requirements:  

  • Ph.D. with 0-3 years of industrial experience or Master degree with a minimum of 3 years of relevant experience in pharmaceutical, biopharmaceutical, and/or vaccine development.
  • A thorough understanding of protein chemistry, protein post-translational modifications, protein-ligand binding, protein-protein interactions, and methods used for higher order structure analysis.
  • Strong understanding of mass spectrometric, electrophoretic, and chromatographic techniques in protein and carbohydrate characterization.
  • Ability to critically analyze data, to communicate results, and to author technical reports.
  • Excellent record keeping abilities to document analytical data generated in support of regulatory requirements.
  • Ability to work effectively in cross-functional groups.

Novavax, Inc. (Nasdaq: NVAX) is a clinical-stage biopharmaceutical company creating novel vaccines to address a broad range of infectious diseases worldwide. Using innovative virus-like particle (VLP) and recombinant nanoparticle technology, as well as new and efficient manufacturing approaches, the company produces potent vaccine candidates to combat diseases, with the goal of allowing countries to better prepare for and more effectively respond to rapidly spreading infections. Novavax is committed to using its technology platforms to create geographic-specific vaccine solutions and is therefore involved in several international partnerships, including collaborations with Cadila Pharmaceuticals of India and LG Life Sciences of Korea. Together, these companies have worldwide commercialization capacity and the global reach to create real and lasting change in the biopharmaceutical field.

Novavax, Inc. offers a base salary, annual bonus, stock options, professional career development/growth opportunities, and a comprehensive benefits package including medical, dental, vision, Rx, STD, LTD, Life, Optional Life, 401(k) plan.

We are an equal opportunity employer that values diversity at all levels. All individuals, regardless of personal characteristics, are encouraged to apply.

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